1. Optical coherence tomography and cognitive dysfunction in Parkinson disease

    Optical coherence tomography and cognitive dysfunction in Parkinson disease

    Background Parkinson’s disease (PD) is a progressive neurodegenerative disease of aging. Optical coherence tomography (OCT) is a simple noninvasive imaging technique to estimate the retinal nerve fiber layer (RNFL) thickness. The aim of this study is to measure the changes of the RNFL thickness in patients with Parkinson disease in comparison with the control group and to detect the relationship between these changes in RNFL with cognitive functions and physical disability in Parkinson patients. Methods 20 PD patients (40 eyes) and 20 healthy persons (40 eyes) were enrolled according to the defined criteria. The diagnosis of the patient's ...

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