1. SPECTRAL CALIBRATION FOR SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY BASED ON B-SCAN DOPPLER SHIFT WITH IN SITU. TISSUE IMAGES (Thesis)

    SPECTRAL CALIBRATION FOR SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY BASED ON B-SCAN DOPPLER SHIFT WITH IN SITU. TISSUE IMAGES (Thesis)

    We propose a simple method of linearizing spectral interference fringes of spectral domain optical coherence tomography (SDOCT) based on B-scan Doppler frequency shift (DFS), which can be obtained by offsetting the laser beam from the pivot of a scanning mirror. We show that DFS is proportional to wavenumber. A DFS curve can be then extracted from either a single mirror image or multiple tissue images. By examining the convergence of the nonlinear coefficients of the DFS curve fitted with a polynomial equation, in situ. tissue images themselves can be used to linearize the wavenumber without requiring mirror images or additional ...

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