1. Diagnostic accuracy of spectral domain optical coherence tomography circumpapillary, optic nerve head and macular parameters in the detection of perimetric glaucoma

    Diagnostic accuracy of spectral domain optical coherence tomography circumpapillary, optic nerve head and macular parameters in the detection of perimetric glaucoma

    Objective To evaluate the diagnostic accuracy of circumpapillary retinal nerve fibre layer (cRNFL), optic nerve head and macular parameters for the detection of glaucoma using Heidelberg Spectralis optical coherence tomography (OCT). Design Cross-sectional study. Participants Participants of the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) with a vertical cup to disc ratio (VCDR) ≥0.7 and/or VCDR asymmetry ≥0.2 and/or vertical neuroretinal rim ratio (NRRR) ≤0.1 and/or intraocular pressure (IOP) ≥ 25 mmHg were invited to attend the study. Methods Participants underwent clinical examination by a masked glaucoma expert and full-threshold visual field ...

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