1. Optical coherence tomography: seeing the unseen

    Optical coherence tomography: seeing the unseen

    ptical coherence tomography (OCT) is an imaging technology that has revolutionised the way we detect and manage ocular disease. Quite simply, it allows the clinician to visualise ocular pathology previously not detectable or only evident in advanced disease. OCT has its roots in ultrafast laser‐activated shutters to photograph ‘light echoes’, which allowed the depth of objects to be captured. Duguay and Mattick 1 at AT&T Bell Laboratories in 1971 suggested this technique could be applied to ‘see inside’ biological tissue. In the 1980s, low‐coherence interferometry was used to measure ‘light echoes’ and had its first in vivo ...

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