1. Line-Field Optical Coherence Tomography as a tool for In vitro characterization of corneal biomechanics under physiological pressures

    Line-Field Optical Coherence Tomography as a tool for In vitro characterization of corneal biomechanics under physiological pressures

    There has been a lot of interest in accurately characterising corneal biomechanical properties under intraocular pressure (IOP) to help better understand ocular pathologies that are associated with elevated IOP. This study investigates the novel use of Line-Field Optical Coherence Tomography (LF-OCT) as an elastographic tool for accurately measuring mechanical properties of porcine corneas based on volumetric deformation following varying IOPs. A custom-built LF-OCT was used to measure geometrical and corneal surface displacement changes in porcine corneas under a range of IOPs, from 0–60 mmHg. Corneal thickness, elastic properties and hysteresis were calculated as a function of pressure. In addition ...

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