1. Detecting eye and brain disease earlier

    Detecting eye and brain disease earlier

    The eyes may be the window to the soul, but to scientists, they are also the window to the brain. In particular, the retina, a delicate light-sensing neural network with specialized cells at the back of the eyeball, is linked directly to the brain via the optic nerve and is considered by some to be part of the brain itself. Xincheng Yao (Photo: Jenny Fontaine) Now, researchers at the University of Illinois at Chicago are developing imaging techniques that will allow them to study minute changes in the retina that indicate the early stages of brain diseases like Alzheimer’s ...

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    1. We can’t use functional OCT/OCTA in the brain to look at neurovascular coupling at the cellular level because the brain is surrounded by the skull, and fine resolution isn’t possible...But we can use functional OCT/OCTA to examine the interactions between individual photoreceptors and their blood vessels in the retina, which is much more accessible in the eye.
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