1. Toward optical coherence tomography angiography-based biomarkers to assess the safety of peripheral nerve electrostimulation

    Toward optical coherence tomography angiography-based biomarkers to assess the safety of peripheral nerve electrostimulation

    Objective: Peripheral nerves serve as a link between the central nervous system and its targets. Altering peripheral nerve activity through targeted electrical stimulation is being investigated as a therapy for modulating end organ function. To support rapid advancement in the field, novel approaches to predict and prevent nerve injury resulting from the electrical stimulation must be developed to overcome the limitations of traditional histological methods. The present study aims to develop an optical imaging-based approach for real-time assessment of peripheral nerve injury associated with electrical stimulation.
 
 Approach: We developed an optical coherence tomography angiography system and a 3-D ...

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