1. Integrated multimodality intravascular imaging system that combines optical coherence tomography, ultrasound imaging, and acoustic radiation force optical coherence elastography

    Integrated multimodality intravascular imaging system that combines optical coherence tomography, ultrasound imaging, and acoustic radiation force optical coherence elastography

    An integrated intraluminal imaging system includes an optical coherence tomography interferometer (OCT), an ultrasound subsystem (US) and a phase resolved acoustic radiation force optical coherence elastography subsystem (PR-RAF-OCE). The steps include performing OCT to generate a returned optical signal, performing US imaging to generate a returned ultrasound signal, performing PRARF-OCE to generate a returned PR-ARF-OCE signal by generating a amplitude modulated ultrasound beam or chirped amplitude modulated ultrasound beam to frequency sweep the acoustic radiation force, measuring the ARF induced tissue displacement using phase resolved OCT, and the frequency dependence of the PR-ARF-OCE signal, processing the returned optical signal, the ...

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