1. Optical Coherence Tomography Segmentation Errors of the Retinal Nerve Fiber Layer Persist Over Time

    Optical Coherence Tomography Segmentation Errors of the Retinal Nerve Fiber Layer Persist Over Time

    Précis: There are errors in automated segmentation of the retinal nerve fiber layer in glaucoma suspects or patients with mild glaucoma that appear to persist over time; however, automated segmentation has greater repeatability than manual segmentation. Purpose: To identify whether optical coherence tomography (OCT) segmentation errors in retinal nerve fiber layer (RNFL) thickness measurements persist longitudinally. Methods: This was a cohort study. We used spectral domain OCT (Spectralis, Heidelberg Engineering, Heidelberg, Germany) to measure RNFL thickness in a 6-degree peripapillary circle, and exported the native “automated segmentation only” results. In addition, we exported RNFL thickness results after “manual refinement ...

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