1. Impact of MEditerranean Diet, Inflammation and Microbiome After an Acute Coronary Syndrome

    Impact of MEditerranean Diet, Inflammation and Microbiome After an Acute Coronary Syndrome

    In the MEDIMACS project, we will use a randomized clinical-trial design to address the effects of mediterranean diet on atherosclerotic plaque vulnerability and coronary endothelial function in order to decipher complex interplays between diet, microbiome, immunological and metabolic responses and coronary atherosclerosis. We will focus on patients after an episode of acute coronary syndrome and use state-of-the-art techniques to address atherosclerotic plaque composition and coronary endothelial function. A number of different -omic approaches will be used to address effector pathways. The insights provided by this study will allow identifying potential new dietary, microbiota and/or metabolic targets for the treatment ...

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