1. Predictive Model for Macular Hole Closure Speed: Insights From Intraoperative Optical Coherence Tomography

    Predictive Model for Macular Hole Closure Speed: Insights From Intraoperative Optical Coherence Tomography

    Purpose : To establish a predictive model of macular hole (MH) closure speed. Methods : This study was a post hoc analysis of eyes that underwent full-thickness MH repair in the prospective PIONEER intraoperative optical coherence tomography (iOCT) study. The Bioptigen SDOIS system was used for iOCT imaging. All patients underwent standard small-gauge vitrectomy with internal limiting membrane (ILM) peeling, gas tamponade, and postoperative facedown positioning. Before vitrectomy and after ILM peeling, various quantitative OCT measures related to MH were obtained, including MH geometry alterations and outer retinal features. Trans-gas OCT was performed on postoperative day 1 to evaluate MH closure. Univariate ...

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