1. Optical coherence tomography imaging of presumed Cryptococcus neoformans infection localized to the retina

    Optical coherence tomography imaging of presumed Cryptococcus neoformans infection localized to the retina

    Purpose To report spectral-domain optical coherence tomography (SD-OCT) findings of presumed Cryptococcus neoformans infection limited to the retina . Methods We report a 39-year-old male with decreased vision for 3 months. Clinical examination revealed multiple cream-colored retinal lesions in the posterior pole of both eyes. SD-OCT demonstrated multiple areas of discrete, hyperreflective deposits in the inner retina, outer retina, and subretinal space without evidence of choroidal involvement. Fundus autofluorescence demonstrated areas of hyperautofluorescence of lesions with variable areas of hypoautofluorescence. Results Subsequent laboratory workup revealed systemic Cryptococcus neoformans infection. After 3 months of systemic antifungal treatment and follow-up, there was clinical ...

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