1. The safety of renal denervation as assessed by optical coherence tomography: pre- and post-procedure comparison with multi-electrode ablation catheter in animal experiment

    The safety of renal denervation as assessed by optical coherence tomography: pre- and post-procedure comparison with multi-electrode ablation catheter in animal experiment

    Objective Prove the effectiveness and safety of multi-electrode ablation catheter in renal denervation (RDN) by optical coherence tomography (OCT). Methods 16 renal arteries were enrolled from 8 pigs. Angiography and OCT were used to obtain the morphology changes before RDN and 1-month follow-up. Blood pressure and creatinine were tested to prove the effectiveness and safety of the catheter. Results 1 renal artery was excluded because of the small diameter. 15 renal arteries were successfully preformed renal denervation and OCT. Mean blood pressure was significantly reduced 1 month after RDN (122.40±3.54mmHg vs 106.50±2.06mmHg, n=8 ...

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