1. A Mechanical Approach for Smooth Surface Fitting to Delineate Vessel Walls in Optical Coherence Tomography Images

    A Mechanical Approach for Smooth Surface Fitting to Delineate Vessel Walls in Optical Coherence Tomography Images

    Automated analysis of vascular imaging techniques is limited by the inability to precisely determine arterial borders. Intravascular optical coherence tomography (OCT) offers unprecedented detail of artery wall structure and composition, but does not provide consistent visibility of the outer border of the vessel due to limited penetration depth. Existing interpolation and surface fitting methods prove insufficient to accurately fill the gaps between the irregularly-spaced and sometimes unreliably-identified visible segments of the vessel outer border. This paper describes an intuitive, efficient, and flexible new method of three-dimensional surface fitting and smoothing suitable for this task. An anisotropic linear-elastic mesh is fit ...

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