1. Multifractal and Lacunarity Analyses of Microvascular Morphology in Eyes with Diabetic Retinopathy: A Projection Artifact Resolved Optical Coherence Tomography Angiography Study

    Multifractal and Lacunarity Analyses of Microvascular Morphology in Eyes with Diabetic Retinopathy: A Projection Artifact Resolved Optical Coherence Tomography Angiography Study

    Objective To evaluate the degree of microvascular impairment in diabetic retinopathy using multifractal and lacunarity analyses and to compare the diagnostic ability between traditional Euclidean measures (fovea avascular zone area and vessel density) and fractal geometric features. Methods This retrospective cross‐sectional study included a total of 143 eyes of 94 patients with different stages of diabetic retinopathy. The retinal microvasculature was imaged by projection removed optical coherence tomography angiography. We examined the degree of association between fractal metrics of the retinal microvasculature and diabetic retinopathy severity. The area under the receiver operating characteristic curve was used to estimate the ...

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