1. Assessing the biomechanical properties of the porcine crystalline lens as a function of intraocular pressure with optical coherence elastography

    Assessing the biomechanical properties of the porcine crystalline lens as a function of intraocular pressure with optical coherence elastography

    In this study, we investigated the relationship between the biomechanical properties of the crystalline lens and intraocular pressure (IOP) using a confocal acoustic radiation force (ARF) and phase-sensitive optical coherence elastography (OCE) system. ARF induced a small displacement at the apex of porcine lenses in situ at various artificially controlled IOPs. Maximum displacement, relaxation rate, and Young’s modulus were utilized to assess the stiffness of the crystalline lens. The results showed that the stiffness of the crystalline increased as IOP increased, but the lens stiffening was not as significant as the stiffening of other ocular tissues such as the ...

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