1. Optical coherence tomography revisited: imaging and imagination

    Optical coherence tomography revisited: imaging and imagination

    Optical coherence tomography (OCT) was introduced into cardiovascular imaging in 1997 1 , emerging as a spin-off from an original scientific invention within the field of ophthalmology to enable imaging of retinal microstructures including arterioles and to facilitate detection of early degenerative changes of retinopathies. Consequently, OCT was praised as being a ground-breaking imaging technology which provides a far superior resolution as compared to the already established ultrasound-based imaging system (intravascular ultrasound [IVUS]). As such, it provides high-resolution tomographic images (10-20 µm), which enable recognition of atherosclerotic plaque patterns 2 , 3 , and can be used to identify high-risk lesions including their ...

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