1. Intravascular optical coherence tomography

    Intravascular optical coherence tomography

    Intravascular optical coherence tomography (IVOCT) began at MIT in the early 1990’s with the recognition that OCT could be used for clinical applications other than ophthalmology. Initial steps made there towards IVOCT feasibility included the acquisition of cadaver arterial images demonstrating the capacity of OCT to visualize depth-resolved architectural detail of plaque 5 and the development of the first mechanical scanning catheter. 6 Early histopathologic correlation studies from cadaver arteries demonstrated that IVOCT was capable of distinguishing the major fibrous, fibrocalcific, and lipid-rich plaque types and also potentially identifying inflammation as manifested by macrophage accumulations. 7, 8 Data from ...

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