1. Non invasive optical cellular imaging in humans

    Non invasive optical cellular imaging in humans

    One of the most appealing and still unsolved problems in biological and medical imaging is the possibility of noninvasive visualization of tissue in vivo with an accuracy of microscopic examination. A major difficulty to solve in biomedical imaging is a degradation of image quality caused by the presence of optical inhomogeneity of tissue. Is there any chance to develop a microscopic method that allows non-invasive observation of cells in living tissue? Classical optical microscopy requires first to retrieve, then to process and finally to stain the sample, which is usually not possible to be performed in vivo. One of the ...

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