Spectral Contrast Optical Coherence Tomography Angiography Enables Single-Scan Vessel Imaging
Optical Coherence Tomography angiography relies on motion for contrast and requires at least two data acquisitions per point-wise scanning location. We present a method termed Spectral Contrast Optical Coherence Tomography Angiography using visible light which relies on the spectral signatures of blood to obtain angiography from a single scan using endogenous contrast. We demonstrate the molecular sensitivity of this method enabling lymphatic, blood, and tissue discrimination.
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