1. Spectral domain-optical coherence tomographic assessment of macular changes following anti-vascular endothelial growth factor therapy in patients with retinopathy of prematurity

    Spectral domain-optical coherence tomographic assessment of macular changes following anti-vascular endothelial growth factor therapy in patients with retinopathy of prematurity

    Aim: The purpose of this study was to investigate the effect of intravitreal ranibizumab (IVR) injection for type 1 and aggressive posterior retinopathy of prematurity (ROP) and to detect probable alterations in central foveal thickness, to analyze macular structural changes and to observe regression of ROP following IVR therapy. Material and Methods: 40 eyes of 22 patients with type 1 or aggressive posterior ROP who received IVR injections and had macular spectral domain– optical coherence tomography (SD – OCT) images were included in the study. All eyes were scanned using a portable SD-OCT machine before treatment and 1st week, 1st month ...

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