1. In vivo imaging of complicated atherosclerotic plaque – role of optical coherence tomography (OCT)

    In vivo imaging of complicated atherosclerotic plaque – role of optical coherence tomography (OCT)

    Cardiovascular diseases are the main cause of death worldwide, with coronary artery disease (CAD) being the predominant underlying etiology. Coronary angiography (CA) is the current invasive method used for CAD diagnosis, as well as for defining the coronary interventional treatment strategy. However, CA offers sometimes-poor accuracy in estimating atherosclerotic plaque volume, morphology and degree of stenosis severity. Optical coherence tomography (OCT) is an intracoronary imaging technique, developed in order to overcome CA limitations and is considered to be an “optical biopsy” that provides in vivo imaging. OCT has an extremely high resolution, similar to that of a usual histological evaluation ...

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