Association of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline A Study Using Optical Coherence Tomography

The JAMA Network Jun 25 2018 Neurology , Ophthalmology

Importance Identifing potential screening tests for future cognitive decline is a priority for developing treatments for and the prevention of dementia. Objective To examine the potential of retinal nerve fiber layer (RNFL) thickness measurement in identifying those at greater risk of cognitive decline in a large community cohort of healthy people. Design, Setting, and Participants UK Biobank is a prospective, multicenter, community-based study of UK residents aged 40 to 69 years at enrollment who underwent baseline retinal optical coherence tomography imaging, a physical examination, and a questionnaire. The pilot study phase was conducted from March 2006 to June 2006, and ...

Read Full Article

Bookmark or Share this article

Login to comment.

Visualization of 3 Distinct Retinal Plexuses by Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy also published in The JAMA Network
A Comparison of Macular Structure Imaged by Optical Coherence Tomography in Preterm and Full-Term Children also categorized in Ophthalmology
Optical Coherence Tomography in the UK Biobank Study – Rapid Automated Analysis of Retinal Thickness for Large Population-Based Studies also written by Paul J. Foster
Changes in Angle Configuration After Phacoemulsification Measured by Anterior Segment Optical Coherence Tomography. also written by Paul J. Foster
Change of foveal and perifoveal thickness measured by OCT after phacoemulsification and IOL implantation also categorized in Ophthalmology
Diagnostic Performance of Anterior Chamber Angle Measurements for Detecting Eyes With Narrow Angles: An Anterior Segment OCT Study: An Anterior Segment OCT Study also written by Paul J. Foster
Optical Coherence Tomography Imaging of Paton Folds in Papilledema With Retinopathy From Systemic Hypertension also published in The JAMA Network
Variation of Angle Parameters in Asians: An Anterior Segment Optical Coherence Tomography Study in a Population of Singapore Malays also written by Paul J. Foster
Spectral-Domain Optical Coherence Tomography Imaging in 67,321 Adults also written by Paul J. Foster
Use of Retinal Optical Coherence Tomography to Detect Congenital Zika Syndrome also published in The JAMA Network