1. Healing by design: in vivo insights following contemporary coronary stent deployment

    Healing by design: in vivo insights following contemporary coronary stent deployment

    The evolution of coronary stenting from bare metal to first- and second-generation drug-eluting stents (DES) has been accompanied by a progressive reduction in major adverse cardiovascular events (MACE) including stent thrombosis, with the greatest differential between these devices occurring during the first year after deployment. 1 Beyond 1 year, clinical events (MACE, target lesion, or vessel failure) occur at a consistent 2–4%/year rate regardless of device. 2 , 3 The pathogenesis of very late events may relate to the common...

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