1. Adapting a commercial spectral domain optical coherence tomography system for time-locked displacement and physiological measurements

    Adapting a commercial spectral domain optical coherence tomography system for time-locked displacement and physiological measurements

    Measuring vibration within the cochlear partition is important to understand sound transduction and nonlinear amplification within the cochlea. Here we describe the customization of a commercially available Spectral Domain Optical Coherence Tomography system, the Thorlabs Telesto, for displacement measurements in the cochlea using a technique called Spectral Domain Phase Microscopy (SDPM). The paper describes the SDOCT data analysis pipeline composed of background subtraction, interpolation, and spectral shaping of the raw photodetector data, followed by the implementation of SDPM for vibration measurements. It also details the software and hardware modification necessary to couple the Telesto to a Tucker-Davis Technologies data acquisition ...

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