1. Evaluating micro-optical coherence tomography (μOCT) as a feasible imaging tool for pancreatic disease diagnosis

    Evaluating micro-optical coherence tomography (μOCT) as a feasible imaging tool for pancreatic disease diagnosis

    Pancreatic cancer is one of the leading causes of cancer mortality worldwide due to the lack of reliable tools for early diagnosis of this cancer. In this study, we evaluated the feasibility of micro-optical coherence tomography (μOCT) as an imaging tool for the diagnosis of pancreatic cancers. Specifically, we constructed a μOCT device that achieves a resolution of ∼1.67 μm and 1.79 μm in axial and lateral directions, respectively, and acquires three-dimensional μOCT images of mouse, rat and human pancreatic specimens ex vivo. We compared the results of μOCT with those of the corresponding histology. In μOCT images ...

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