Two optical coherence tomography systems detect topical gold nanoshells in hair follicles, sweat ducts and measure epidermis

Optical coherence tomography (OCT) is an optical imaging technology that enables real time, high‐resolution, cross‐sectional and en face investigation of skin by detecting reflected broad‐spectrum near‐infrared light from tissue. OCT provides micron‐scale spatial resolution and millimeter‐scale depth of penetration [1]. Several commercial OCT systems with handheld probes targeted for Dermatology are now available [2].
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