1. Multimodal imaging of lung tissue dynamics in mechanically ventilated rats with optical coherence tomography and intravital microscopy

    Multimodal imaging of lung tissue dynamics in mechanically ventilated rats with optical coherence tomography and intravital microscopy

    The understanding of alveolar mechanics is an essential step towards new and more protective ventilation strategies which are of dare need for the treatment of diseases of lung tissue and the airways. Such ailments become a major task for medical care and health care systems in modern industrial countries in the future. Besides the obvious importance as life-saving intervention, the mechanical strain and processes on the level of gas exchange are still insufficiently understood. Therefore, it is of great interest to characterize lung tissue and tissue dynamics during artificial ventilation at the alveolar level. 4D Optical coherence tomography (OCT) in ...

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