1. Two Optical Coherence Tomography Systems detect Topical Gold Nanoparticles in Hair follicles, Sweat Ducts and Measure Epidermis

    Two Optical Coherence Tomography Systems detect Topical Gold Nanoparticles in Hair follicles, Sweat Ducts and Measure Epidermis

    Optical coherence tomography (OCT) is an optical imaging technology that enables real time, highresolution, cross-sectional and en face investigation of skin by detecting reflected broad-spectrum near-infrared light from tissue. OCT provides micron-scale spatial resolution and millimeter-scale depth of penetration [1]. Several commercial OCT systems with handheld probes targeted for Dermatology are now available [2]. The ability of OCT to achieve high diagnostic accuracy in skin diseases is hampered by the fact that not all diseases show sufficient contrast to be discriminated from normal skin. The challenge in realizing contrast enhancement in OCT imaging is to achieve signal from exogenous contrast ...

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