1. In vivo broadband visible light optical coherence tomography probe enables inverse spectroscopic analysis

    In vivo broadband visible light optical coherence tomography probe enables inverse spectroscopic analysis

    We report the design and characterization of a 6 mm outer diameter pull-back circumferential scanning visible optical coherence tomography probe. The probe’s large visible bandwidth (500–695 nm) allowed for inverse spectroscopic analysis and an axial resolution of ∼ 1.1    μm ∼1.1  μm in tissue. We verify spectral imaging capabilities by measuring microsphere backscattering spectra and demonstrate in vivo spatial nanoscale characterization of tissue.

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