1. Biomechanical mapping method aids development of therapies for damaged heart tissue

    Biomechanical mapping method aids development of therapies for damaged heart tissue

    Researchers have developed a new way to capture the detailed biomechanical properties of heart tissue. The high-resolution optical technique fills an important technology gap necessary to develop and test therapies that might eventually be used to heal heart damage after a heart attack. "Today about one million people suffer heart attacks every year, and there is currently no cure for the resulting cardiac tissue scarring," said Kirill V. Larin of University of Houston , Texas who co-led the research with James F. Martin from the Baylor College of Medicine and the Texas Heart Institute . "We are working to develop ways to ...

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    1. Today about one million people suffer heart attacks every year, and there is currently no cure for the resulting cardiac tissue scarring...We are working to develop ways to regenerate heart tissue and our research works to measure the mechanical properties to determine if the heart is healing in response to therapies.
    2. Experiments have shown that tissue from newborn mammalian hearts can completely regenerate, but with age this regeneration capability diminishes...Martin's group is working on ways to manipulate these molecular pathways in a way that stimulates the adult heart tissue to repair itself.
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