1. Automated Detection and Measurement of Corneal Haze and Demarcation Line in Spectral-Domain Optical Coherence Tomography Images

    Automated Detection and Measurement of Corneal Haze and Demarcation Line in Spectral-Domain Optical Coherence Tomography Images

    Keratoconus is a progressive eye disease that may lead to significant loss of visual acuity. Corneal cross-linking (CXL) is a surgical procedure that halts the progression of Keratoconus. One commonly used clinical indicator of CXL success, albeit being an indirect one, is the presence and depth of stromal demarcation line. In addition, corneal haze beyond the demarcation line can be an ominous sign of loss of corneal transparency, which is a much-dreaded side-effect of CXL. To date, ophthalmologists evaluate the presence and depth of the demarcation line, and grade corneal haze using slit lamp biomicroscopy and/or optical coherence tomography ...

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