1. Endothelial Progenitor Cell Biology and Vascular Recovery Following Transradial Cardiac Catheterization

    Endothelial Progenitor Cell Biology and Vascular Recovery Following Transradial Cardiac Catheterization

    Background Transradial catheterization is associated with radial artery injury and vasomotor dysfunction and represents an accessible model of acute vascular injury in humans. We characterized vascular injury and functional recovery to understand the role of circulating endothelial progenitor cells in vascular repair. Methods and Results In 50 patients (aged 64±10 years, 70% male) undergoing transradial cardiac catheterization, radial artery injury was assessed by optical coherence tomography and examination of explanted vascular sheaths. Flow‐ and nitrate‐mediated dilatation of the radial artery was assessed in both arms at baseline, at 24 hours, and at 1, 4, and 12 weeks. Circulating ...

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