1. OCT Angiography Changes in the 3 Parafoveal Retinal Plexuses in Response to Hyperoxia

    OCT Angiography Changes in the 3 Parafoveal Retinal Plexuses in Response to Hyperoxia

    Purpose Use projection-resolved OCT angiography to investigate the autoregulatory response in the 3 parafoveal retinal plexuses under hyperoxia. Design Prospective cohort study. Participants Nine eyes from 9 healthy participants. Methods One eye from each participant was scanned using a commercial spectral-domain OCT system. Two repeated macular scans (3 × 3 mm 2 ) were acquired at baseline and during oxygen breathing. The split-spectrum amplitude-decorrelation algorithm was used to detect blood flow. The projection-resolved algorithm was used to suppress projection artifacts and resolve blood flow in 3 distinct parafoveal plexuses. The Wilcoxon signed-rank test was used to compare baseline and hyperoxic parameters. The ...

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