1. Advances in intraoperative optical coherence tomography for surgical guidance

    Advances in intraoperative optical coherence tomography for surgical guidance

    Translation of optical coherence tomography (OCT) technologies for intraoperative visualization enables in vivo micron-resolution imaging of subsurface tissue structures and image-guided clinical decision-making. Over the last decade, intraoperative OCT has evolved from two-dimensional imaging using handheld probes to include biopsy-needles for minimally invasive deep-tissue imaging, surgical instrumentation using optical feedback for tremor dampening and stabilization, and stereomicroscope integrated systems that provide real-time three- and four-dimensional visualization of surgical maneuvers. In addition, several preliminary studies have demonstrated the feasibility and utility of combining intraoperative OCT imaging with novel image-processing and display methods to implement augmented/virtual reality and robotic surgical guidance ...

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