1. Cellular Characterization of Optical Coherence Tomography and Outer Retinal Bands Using Specific Immunohistochemistry Markers and Clinical Implications

    Cellular Characterization of Optical Coherence Tomography and Outer Retinal Bands Using Specific Immunohistochemistry Markers and Clinical Implications

    Purpose Optical coherence tomography has been a technological breakthrough in the diagnosis, treatment, and follow-up of many ocular diseases, especially retinal and neuro-ophthalmologic pathologic conditions. Until now, several controversies have arisen over the specific cell types that the bands observed in the OCT represent, especially over the 4 outer retinal bands. Design To correlate the 4 outer hyperreflective bands observed in the OCT with the histologic structures using human retinal sections and immunocytochemistry at the fovea level. Participants Eyes from human donors. Methods Vertical cryosections of human retinas were immunostained with antibodies specific for cones photoreceptors, bipolar cells, mitochondria, M ...

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