1. Comparison of Accuracy of One Use Methods for Calculating Fractional Flow Reserve by Intravascular Optical Coherence Tomography to That Determined by the Pressure-Wire Method

    Comparison of Accuracy of One Use Methods for Calculating Fractional Flow Reserve by Intravascular Optical Coherence Tomography to That Determined by the Pressure-Wire Method

    While identification of hemodynamic significance of coronary lesions becomes important for revascularization strategy, the potential role of three-dimensional high-resolution intracoronary Optical coherence tomography (OCT) for predicting functional significance of coronary lesions remains unclear. We assessed the diagnostic performance of two computational approaches for deriving fractional flow reserve (FFR) from intravascular OCT images. We developed two methods to derive FFR from volumetric OCT images by applying analytical fluid dynamics (FFR-OCTAFD) and computational fluid dynamics (FFR-OCTCFD). Among 217 eligible patients between 2011 and 2014, total 104 patients were included for data analysis (9 for derivation, 95 for validation). Luminal geometries from three-dimensional ...

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