1. Impact of Cigarette Smoking and Smoking Cessation on Stent Changes as Determined by Optical Coherence Tomography after Sirolimus Stent Implantation

    Impact of Cigarette Smoking and Smoking Cessation on Stent Changes as Determined by Optical Coherence Tomography after Sirolimus Stent Implantation

    There is debate regarding whether smoking results in microstructural changes after stenting. The aim of this study was to evaluate the microstructural changes after stenting in patients with different smoking statuses. We retrospectively identified 220 sirolimus-eluting stents in 179 patients who underwent follow-up optical coherence tomography examination 12 months after sirolimus stenting. Subjects were classified as current smokers (CS, n=31), smoking cessation ≤1 year (SC1Y, n=36), smoking cessation >1 year (SC>1Y, n=27) and never smokers (NS, n=85). The neointimal hyperplasia (NIH) area was larger in CS than NS (1.04±0.72 mm 2 versus ...

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