1. Optical Coherence Tomography Imaging of a Large Spherical Seed in Retinoblastoma

    Optical Coherence Tomography Imaging of a Large Spherical Seed in Retinoblastoma

    The clinical applications of handheld optical coherence tomography (OCT) imaging (Bioptigen, Morrisville, NC) for retinoblastoma continue to evolve and include characterization of small tumors, tumor recurrences, evaluation of seeding, and retinal anatomy. OCT was performed at staging examination of the left eye in a 13-month-old child diagnosed with bilateral retinoblastoma (Group C right eye, Group D left eye) demonstrated normal foveal architecture, preretinal dusting of small hyper-reflective seeds, and a hollow reflective cystic structure floating above the retina, with shadowing posteriorly, which correlated clinically with a large translucent spherical seed in the vitreous cavity (Fig 1, asterisk).

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