1. An automated framework to quantify areas of regional ischemia in retinal vascular diseases with OCT angiography

    An automated framework to quantify areas of regional ischemia in retinal vascular diseases with OCT angiography

    In this observational and cross-sectional study, capillary non perfusion (CNP) and vascular changes in branch retinal vein occlusion (BRVO, sample size (n) = 26) and choroidal neovascularization (CNV, n = 29) were evaluated. Subjects underwent imaging using Optical coherence tomography angiography (Angiovue™ OCTA , RTVue XR, Optovue Inc., Fremont, CA). Local fractal analysis was applied to the OCTA images of superficial, deep and choriocapillaries layer. CNP area (BRVO eyes) and vascular parameters were computed using local fractal based method. Sensitivity and specificity of vascular parameters was assessed with receiver operating characteristics (ROC) curve. Automated CNP area showed excellent agreement with manually quantified CNP ...

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