1. Rapid ex vivo examination of Mohs specimens using optical coherence tomography

    Rapid ex vivo examination of Mohs specimens using optical coherence tomography

    Background Mohs micrographic surgery (MMS) is an effective treatment for certain non-melanoma skin cancers. Optical coherence tomography (OCT) is a biomedical imaging modality that permits high-resolution imaging of the epidermis and dermis with the potential to detect both healthy tissue and tumour. OCT may also provide a means of detecting and differentiating between the various histological subtypes of basal cell carcinomas (BCC) in vivo . Objective : The aim of this prospective ex vivo study was to evaluate the efficacy of OCT in recognising healthy and pathological margins of excised BCC lesions and detecting different BCC subtypes. Methods Seventy-three subjects with biopsy-proven ...

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