Research Associate in Biomedical Optics and Inverse Problems at University College of London
University College London - Department of Medical Physics & Biomedical Engineering Biomedical Optics Research Laboratory (BORL)
UCL’s Department of Medical Physics and Biomedical Engineering conducts internationally leading research across a broad range of biomedical imaging techniques. Funding has recently been awarded to undertake an exciting pilot project known as computed microscopy. This project is a collaboration between the department’s Biomedical Optics Research Laboratory (BORL) and Centre for Medical Image Computing (CMIC) and could have a significant impact upon the fields of optical microscopy and optical coherence tomography.
The core aim of the project is to solve the inverse problem of optical coherence tomography (OCT) using an iterative forward model of OCT image formation in a rigorous manner. Achieving this could lead to improved contrast and sensitivity in OCT when imaging diseased tissue. It could also allow for the restoration of images acquired alongside the OCT image, but using a different modality such as fluorescence microscopy. The principal investigator of this BBSRC funded project (Dr Peter Munro) has developed a three-dimensional model of OCT image formation based on the pseudo-spectral time-domain method. This is currently the most advanced model of OCT image formation applicable to general samples. Prof. Simon Arridge is a co-investigator on the project and is a pioneer of the application of inverse problems to biomedical imaging, having demonstrated the solution to, amongst others, the inverse problem of diffuse optical tomography. This project will thus be managed by both Dr Munro and Prof. Arridge in order to meet the specific aims of the BBSRC project proposal. The post holder will be expected to undertake research into the ill-posedness of the general OCT inverse problem and research to find approaches to improve the ill-posedness of the OCT inverse problem, such as the use of prior-information, measurement schemes etc. The post holder will use existing pseudo-spectral time-domain electromagnetic scattering code (written in C) to demonstrate the solution of an inverse scattering problem for synthetic data using an iterative approach.
The position is available for 17 months in the first instance.
Applicants must hold, or be about to receive, a PhD in electrical engineering, optical or electromagnetic physics, inverse problems, or a closely related field. Applicants should demonstrate a publication record appropriate to their level of experience. Applicants should have experience in some, or all of: pseudo-spectral time-domain or finite-difference time-domain methods, imaging theory, optical coherence tomography and inverse problems. Experience of programming in C/C++ is preferable, however, some level of programming experience in a low-level programming language (eg, C/C++, Java, Fortran etc.) is essential. Appointment at Grade 7 is dependent upon having been awarded a PhD. If about to submit a PhD, the appointment will be at Grade 6B (£29,809 - £31,432) salary per annum (inclusive of London Allowance) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.
Applicants should apply online. To access further details about the position and how to apply please click on the ‘Apply’ button below.
Successful candidates will join the Biomedical Optics Laboratory and Centre for Medical Image Computing at UCL. Further information on the research activities of the department can be found at: http://www.ucl.ac.uk/medphys/research . For informal inquiries, please contact Dr Peter Munro ( email@example.com ) or Prof. Simon Arridge ( firstname.lastname@example.org ). If you have any queries regarding the application process please contact Tracy Pearmain on email@example.com
Interview Date: TBC
Vacancy number 1648144.
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