1. Fundus autofluorescence in the buried optic disc drusen: optical coherence tomography findings

    Fundus autofluorescence in the buried optic disc drusen: optical coherence tomography findings

    Optic disc drusen (ODD) is hyaline material within the disc that frequently shows flecks of calcium. 1 Electron microscopic examination revealed that ODD is composed of aggregates of extracellular mitochondria containing calcium crystals. 2 Most diagnostic methods, such as B-scan ultrasonography and computed tomography, focus on the calcification signal. 3 However, calcification is not always detectable, as seen in the buried ODD. 4 Spectral-domain optical coherence tomography (SD-OCT) enables the acquisition of cross-sectional images of the optic nerve head with ODD. 5 , 6 , 7 Notably, SD-OCT can capture the margin of ODD without definite calcification. 5 , 6 ODD in childhood ...

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