Ultra-deep imaging of optical coherence tomography in highly scattering media

A time-domain optical coherence tomography system based on measuring the reflection matrix of back-scattered light is proposed for extended imaging depth into scattering media. A filtering operation is applied to the reflection matrix to preserve the back-scattered light with near-forward directions while discarding most of the multiple scattered light. A singular value decomposition is then carried out in the filtered matrix for principal component analysis, to remove the residual multi-scattered light. The results show the near-forward propagating single scattered light, which is mostly discarded in conventional OCT, can be separated computationally to increase the penetration depth of OCT.
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