1. Quantitative Analysis of Retinal Structure using Spectral Domain Optical Coherence Tomography in RPGR-associated Retinopathy

    Quantitative Analysis of Retinal Structure using Spectral Domain Optical Coherence Tomography in RPGR-associated Retinopathy

    Purpose Quantification of retinal structure and progression using spectral-domain optical coherence tomography (SDOCT) in patients with retinitis pigmentosa (RP) associated with retinitis pigmentosa GTPase regulator gene ( RPGR ) mutations Design Retrospective observational case series Methods Setting: Moorfields Eye Hospital, London, United Kingdom. Subjects: Both eyes of 32 patients. SDOCT follow-up period of >1 year (3.1±1.4 years). Outcome measures: Ellipsoid zone (EZ) width (EZW), outer nuclear layer (ONL) and inner retinal layer (IRL) thickness measurements. Progression rates, interocular symmetry, association with age and genotype were investigated. Results: Significant differences were observed between baseline and final measurements of EZW and ...

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