1. Optimal selection of laser modulation parameters in photothermal optical coherence tomography

    Optimal selection of laser modulation parameters in photothermal optical coherence tomography

    Photothermal optical coherence tomography (PT-OCT) employs a secondary intensity-modulated photothermal laser to create modulated thermal strains that cause variations of the refractive index in the proximity of absorbing chromophores. These variations are directly detected with phase-sensitive OCT and offer insight to the molecular composition and thermo-elastic properties of the sample. Here, we define optimal PT laser modulation parameters by investigating the effect of PT laser power and modulation frequency on the ensuing thermal waves and thermal waves’ impact on the spatial resolution of PT-OCT imaging based on numerical simulations of PT-OCT and samples containing point absorbers.

    Read Full Article

    Login to comment.

  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics Mentioned

  3. Authors