1. Detailed Phenotyping and Characterization of Choroidal Morphological and Vascular Features in Young Men with High Myopia Using Spectral-Domain Optical Coherence Tomography

    Detailed Phenotyping and Characterization of Choroidal Morphological and Vascular Features in Young Men with High Myopia Using Spectral-Domain Optical Coherence Tomography

    Purpose To describe detailed morphological and vascular features of the choroid in eyes with high myopia. Design Cross-sectional study. Methods 515 eyes of young men (mean age 21.59±1.15) years) with high myopia (defined as -6.0 D or worse, mean spherical equivalent -8.66±2.00 D) and 88 controls with emmetropia in both eyes underwent choroidal imaging using spectral domain optical coherence tomography with enhanced depth imaging (EDI-OCT). Raw OCT images were loaded on a custom-written application on MATLAB that enabled delineation for detailed morphological and vascular analyses, including the distance of thickest point from the ...

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