1. Fibrous Caps with Excessive Macrophage Infiltration in Culprit Lesions of Patients with Acute Coronary Syndromes are Associated with Increased Local Temperature

    Fibrous Caps with Excessive Macrophage Infiltration in Culprit Lesions of Patients with Acute Coronary Syndromes are Associated with Increased Local Temperature

    Background: Optical coherence tomography (OCT) provides detailed analysis of the morphological characteristics of the culprit lesion (CL) and determines macrophage density within fibrous caps. Intracoronary thermography (ICT) detects the local inflammatory activation of the CL. We investigated the correlation between morphological and functional characteristics of the CL as analysed by OCT and ICT in patients with acute coronary syndromes (ACS). Methods: We studied 31 CL of 31 pts (mean age 61±14 years) with ACS. We measured by ICT the temperature difference between the lesion and the healthy proximal vessel wall (T). Thereafter, we measured the minimal thickness of the ...

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