1. Plasma treatment effect on angiogenesis in wound healing process evaluated in vivo using angiographic optical coherence tomography

    Plasma treatment effect on angiogenesis in wound healing process evaluated in vivo using angiographic optical coherence tomography

    Non-thermal atmospheric pressure plasma holds promise for promoting wound healing. However, plasma-induced angiogenesis, which is important to better understand the underlying physics of plasma treatment effect on wound healing, remains largely unknown. We therefore evaluated the effect of non-thermal plasma on angiogenesis during wound healing through longitudinal monitoring over 30 days using non-invasive angiographic optical coherence tomography imaging in vivo . We demonstrate that the plasma-treated vascular wound area of mouse ear was noticeably decreased as compared to that of control during the early days in the wound healing process. We also observed that the vascular area density was increased in ...

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