1. Estimating OCT Structural Measurement Floors to Improve Detection of Progression In Advanced Glaucoma

    Estimating OCT Structural Measurement Floors to Improve Detection of Progression In Advanced Glaucoma

    Purpose “Floor effects” in retinal imaging are defined as the points at which no further structural loss can be detected. We estimated the measurement floors for spectral-domain optical coherence tomography (SD-OCT) measurements and compared global change over time in advanced glaucoma eyes. Design Validity study to investigate measurement floors. Methods A longitudinal “Variability Group” of 41 eyes with moderate to advanced glaucoma (SAP MD ≤ -8 dB) was used to estimate measurement floors. Minimum rim width (MRW), ganglion cell-inner plexiform layer thickness (GC-IPLT) and circumpapillary retinal nerve fiber layer thickness (cpRNFLT) were determined. Floors were defined as the average image area ...

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